MIAC - Medical Image Analysis Center

Your study. Our expertise.

Customized data analysis for your study, with our expertise and commitment for quality.

Brain Volumes

MIAC herewith announces the implementation of MIAC Brain Volumes. Our new web application provides volumetric brain analysis and will be available on our website as of mid February.

MRI Academy 2019

In 2019, we will again organize our well-established MRI Academy. Contact us for more information on this highly specialized and interactive training course for clinicians in neurology and radiology.

MIAC at ECTRIMS 2018

Tim Sinnecker presented his research on central vein signs at the annual ECTRIMS congress in Berlin and was selected as one of the congress highlights. Go to the interview.

About Us

Since 1995, MIAC has been committed to deliver fully-personalized data analysis for pharmaceutical and academic research.

Advanced image analysis technologies and high impact scientific outcomes for your international trial with our expertise and commitment for personalized customer service.

Tailor-made data analysis pipelines in Swiss quality standards ensure custom metrics and transparent gapless data safety for your imaging study.

The Medical Image Analysis Center (MIAC) is a clinical research organisation supporting international trials with advanced image acquisition and analysis technologies. As an academic corporation that was founded at the Basel University Hospital in 1995, MIAC today is tightly embedded in a national and international institutions and research network, driving the translation of novel imaging and post-processing modalities from development to application in clinical trials.


A highly specialized team of board-certified neuro-/radiologists, physicists, biomedical engineers, IT specialists, technicians and clinicians deliver tailor-made image data analysis services and international trial support to the leaders of the pharmaceutical industry.


All MIAC services follow the high standards of Swiss quality and comply with the requirements of FDA – 21 CFR Part 11 & ICH – Good Clinical Practices.

Clinical Trials

MIAC provides an extensive suite of services to successfully plan, organize, and lead your international trial.

MIAC is your certified partner and reference center for phase II, III and IV trials and has been analyzing international key studies for more than two decades, establishing a well-cited track record with scientific and commercial partners.

Project Planning

Study Hosting

Image Analysis

Output & Performance

Project Planning

Our in-house specialists of board-certified neuro-/radiologists, experienced MR physicists, MR technicians and image analysis experts provide an extensive support in planning and setting-up your study, identifying the most relevant outcome biomarker(s) and designing state of the art analysis pipelines that include all necessary validation and quality assurance steps.

Study Hosting

At MIAC, we benefit from over 25 years experience in designing and conducting imaging protocols in scientific and clinical trials, from small pilot projects to large world-wide phase III trials on all continents. We provide 24/7 support for every aspect of your study, from site selection, technical assistance to quality assurance, 365 days a year. Our long-term expertise and know-how in data management allows us to assist you to safely collect, manage and store your data in a secured environment easily accessible via our study specific web portals.

Image Analysis

We offer standard and custom analyses for every kind of medical image data (i.e. MRI, CT, PET, OCT) including advanced / future modalities (i.e. ultralow and ultrahigh field MRI, MR fingerprinting, MR elastography). Our extensive library of studies, validated workflows and data management pipelines ensure quantitative, structural and functional image analyses in highest quality and reliability. In addition to routine quantification algorithms, we aim to provide tailored in-house solutions for every imaging aspect of your specific study.

Output & Performance

Our webportal enables you to monitor your study progress in real-time, providing you with a comprehensive overview and full control of the study process. Our experienced staff of scientists, neuro-/radiologists, MR physicists and image analysis experts gladly assist you in achieving an optimal trial outcome. We personally support each participating site world-wide during the trial, contribute to scientific and statistical analyses, and provide personal guidance for the interpretation and summary of study results aiming at high impact publications.

Research

MIAC covers a wide range of research activities in the field of medical imaging.

Our in-house research unit is embedded in a national and international network driving the translation of novel imaging and post-processing modalities from development to applications in clinical trials. MIAC closely collaborates with the qbig (Quantitative Biomedical Imaging Group), the AMT (Adaptable MRI Technology) lab, the CIAN (Center for medical Image Analysis and Navigation), and the ThINk (Translational Imaging in Neurology) group at the Department of Biomedical Engineering at University Basel.

Image-based biomarkers pipelines

Morphometry and quantitative modeling: MIAC efforts focus on developing and combining morphometric markers, which allow for (automated) digital image processing in the context of large multi-center studies.

Imaging phenotypes: Our work aims to detail the morphology of various brain lesions by using advanced neuroimaging techniques to establish new diagnostic and prognostic imaging biomarkers.

Data standardization and homogenization pipelines

Data preparation and processing paradigms: MIAC is developing systems and platforms that support building and using tailored image processing tasks in a standardized modular framework.

Phantom design: MIAC efforts focus on building a modular framework for the construction of 3D-printed brain phantoms, which realistically mimic both anatomy and imaging properties of human brain regions.

Advanced tissue characerization

Arterial spin labeling perfusion and permeability: Our current research focuses on assessing changes in brain perfusion or permeability using an optimized ASL protocol.

MR elastography: MIAC efforts currently focus on defining, optimizing and validating MR elastography protocols to finally evaluate its clinical performance in assessing disease progression or treatment response.

Quantitative contrast mechanisms and ultrahigh field imaging: We integrate advanced neuroimaging techniques such as ultrahigh field MRI at 7 Tesla, quantitative contrast mechanisms and artificial intelligence powered automated segmentation methods to better detect and understand neurodegeneration.

Functional imaging

Functional imaging: The analyses of changes in brain activity allow us to study the neuronal plasticity induced by clinical interventions in both healthy subjects and clinical populations.

Jobs

Join our team.

Are you interested in joining us and contributing to our team success? We are looking forward to receiving your application and to getting to know you soon. Please send your full application including your CV, Motivation Letter and References to our HR department.

Working at MIAC

Neuro- / Radiologist

Scientific Data Analyst

Chief Operation Officer

Working at MIAC

We are looking to appoint a Neuro- / Radiologist (m / f), a Scientific Data Analyst (m / f) to lead our big data management and a Chief Operation Officer (m / f ), all on a permanent basis. Please click at a job title on the left to find more information.

Neuro- / Radiologist

What this role implies:

  • Medical safety reading, incidental finding reporting, medical responsibility of clinical trial analyses, final data review and supervision of a highly experienced analysis team
  • Execution of international research projects
  • Quality control
  • Final and medical review 
  • Teaching and instruction of the study team in data analyses and post-processing routines and (neuro-) radiological differential diagnoses
  • Collaboration in various scientific projects

Who you are:

  • Board Certified radiologist or neuroradiologist
  • Neuroanatomical knowledge
  • Experience in the radiological conduct and evaluation of phase II-IV clinical trials (MRI, CT, (PET)), with focus on neuroradiology (dementia, MS, stroke, oncology) and visceral and musculo-skeletal radiology)
  • Situational awareness, diplomacy, analytical and innovation skills, proactive thinking, leading skills, team- & bridge-building skills, fluent communication skills in English, German of advantage

What we offer:

  • Location Basel, Switzerland
  • Working time 50 - 100 % (flexible working hours)
  • Contract Permanent 
  • Job Level Individual Contributor
  • Job Type Regular Employee

Scientific Data Analyst

What this role implies:

  • Propose, develop and validate new approaches using cutting-edge methods as well as optimize and customize pre-existing tools for basic and advanced MRI data processing
  • Setting up procedures to analyze data (e.g. phase III clinical trials in Multiple Sclerosis), coordinate and perform quality assessment to ensure high quality and reliable results in cooperation with various teams
  • Design, conduct and publish projects to provide support to processes applied
  • Cooperate with our customers in the pharmaceutical industry and present analyses performed and related results; consult statistical teams to provide background and insights to their analysis
  • Supervise PhD students
  • Consult other team members and external collaborators on image processing and data science topics

Who you are:

  • Master´s or PhD degree in biomedical engineering, computer science, psychics, computational neuroscience, quantitative psychology or related field
  • Experience in the pharmaceutical or clinical environment of advantage
  • Proficient with multiple neuroimaging analysis platforms (e.g. HCP Pipeline, FreeSurfer, SPM, FSL AFNI, GIFT)
  • Strong programing skills and comfort with diverse computing environments (e.g. MatLab, Python, UNIX / BASH languages
  • Strong background in statistics and statistical software scripting (e.g. R, Python)
  • Experience with data visualization
  • Good organizational skills
  • Able to work under pressure and flexible in adapting to changing priorities
  • Diligent and tenacious work approach
  • Residence in Basel of advantage

What we offer:

  • Location Basel, Switzerland
  • Working time 100 % (flexible working hours)
  • Contract Permanent 
  • Job Level Individual Contributor
  • Job Type Regular Employee

Chief Operation Officer

What this role implies:

  • Leading daily Operations Management following predefined strategic goals 
  • Providing improvement on all operational levels, harmonizing and streamlining structures and processes across MIAC 
  • Supervising the financial management system, evaluating investment options and establishing controlling systems
  • Driving innovation to ensure sustainable growth, development and financial stability
  • Supporting the sales activities and strengthen the network of collaboration partners
  • Counseling the management team to take strategic decisions and implementing new structures aligned with the company values and quality standards
  • Ensuring internal knowledge management and efficient workflows by fostering team work and communication
  • Identifying qualification gaps of the employees and defining training measures in collaboration with HR

Who you are:

  • Minimum of 5+ years of business / operations experience (ideally in the pharmaceutical, scientific medical or research environment)
  • At least 3 years’ experience in leading operation teams
  • Degree in Business Administration, Strategic Management, Financial Management or equivalent
  • Hands-on experience in project and change management
  • Knowledgeable to establish and execute long-term strategies
  • Sound financial KPI understanding, proven finance and / or controller background
  • Develop the team and foster team spirit, good mentoring / coaching and communication skills
  • Solution oriented, conceptional and analytical thinking, hands-on mentality
  • Professional knowledge of the English language is imperative
  • Other languages (German) considered beneficial

What we offer:

  • Location Basel, Switzerland
  • Working time 80 % - 100 % (flexible working hours)
  • Contract Permanent 
  • Job Level Management (reports directly to CEO)
  • Travel activity: ca. 20 %

News

Latest news and achievements.

MIAC Brain Volumes

MIAC Brain Volumes

MIAC is pleased to announce Brain Volumes. The software is now online accessible at https://brainvolumes.ch/. With a single registration, you will be able to quantify caudate, hippocampus, palladium, putamen, thalamus, ventricles, CSF and intracranial volumes.